Recombinant Human GM-CSF Protein

Stock: A Stock
Saukewa: GMP-TL302

Tuntube mu

Bayani

Siffofin Bayanai

Halaye

Fayilolin daftarin aiki

Bayanin Samfura

Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) wani muhimmin cytokine ne wanda ke taka muhimmiyar rawa a cikin tsarin hematopoiesis da martani na rigakafi. GM-CSF yana haɓaka bambance-bambance, haɓakawa, da kunna granulocyte da macrophage precursor sel, haɓaka ayyukansu. Wannan furotin yana da mahimmanci don bincike a cikin ilimin rigakafi, ilimin jini, da kuma maganin ciwon daji.

Mabuɗin Siffofin

1.High Purity: Tsarkakewa ta amfani da fasaha na chromatographic na ci gaba, wannan samfurin yana samun matakin tsabta fiye da 95%, yana tabbatar da babban abin dogara da sake sakewa na sakamakon gwaji.

2.High Ayyukan Halittu: An tabbatar da shi ta hanyar gwaje-gwajen ayyuka da yawa, wannan furotin na GM-CSF yana ƙarfafa ƙwayoyin da aka yi niyya sosai, yana tallafawa aikace-aikacen bincike iri-iri da suka danganci aikin ƙwayar cuta da hematopoiesis.

3.Batch Consistency: An samar da shi tare da tsauraran matakan kulawa don tabbatar da daidaito tsakanin batches, rage girman sauye-sauye da haɓaka amincin sakamakon bincike.

4.Animal-Free: An kera shi ba tare da abubuwan da aka samo daga dabba ba, suna bin ka'idodin da ba su da dabba da faɗaɗa amfani da buƙatun bincike daban-daban.

Aikace-aikace

• Hematology: Yi nazarin rawar GM-CSF a cikin tsarin samar da kwayoyin jini, ciki har da granulocytes da macrophages, samar da fahimta game da cututtuka na hematopoietic da hanyoyin kwantar da hankali.

• Immunology: Bincika tasirin GM-CSF akan haɓakar ƙwayoyin rigakafi da kunnawa, yana ba da gudummawa ga zurfin fahimta game da martanin rigakafi da yuwuwar aikace-aikacen warkewa.

• Binciken Ciwon daji: Yi nazarin rawar GM-CSF a cikin ƙananan ƙananan ƙwayoyin cuta da kuma tasirinsa akan aikin ƙwayar cuta, yana ba da basira game da ciwon daji na rigakafi da dabarun magani.

• Magungunan Kwayoyin Halitta: Yi amfani da GM-CSF don haɓaka aiki da fadada ƙwayoyin rigakafi a cikin hanyoyin kwantar da hankali na kwayoyin halitta, ci gaba da bincike a cikin maganin farfadowa da immunotherapy.

Ƙayyadaddun bayanai da Marufi

• Ƙayyadaddun bayanai: Akwai a cikin nau'i-nau'i daban-daban don karɓar buƙatun gwaji daban-daban, ciki har da 10μg, 50μg, 100μg, da 1mg.

• Marufi: An ba da shi a cikin sigar lyophilized bakararre don tabbatar da kwanciyar hankali da sauƙaƙe ajiya mai dacewa da sufuri.

Adana da Kwanciyar hankali

• Adana: Adana a -20°C ko ƙasa don kiyaye kwanciyar hankali na furotin da ayyukan nazarin halittu. A guji maimaita daskarewa-narkewa don hana lalacewa.

• Kwanciyar hankali: Yana da kwanciyar hankali don ajiya na dogon lokaci a ƙarƙashin sharuɗɗan shawarwari, tabbatar da ingantaccen aiki a aikace-aikacen bincike.

Umarnin don Amfani

1.Dissolve da lyophilized foda a cikin madaidaicin buffer mai dacewa a cikin yanayi mara kyau kafin amfani.

2.Shirya da tsarma bayani bisa ga buƙatun gwaji don cimma daidaitattun sakamakon da za a iya sakewa.

3.Avoid hadawa da sauran makamantan kayayyakin don hana giciye-reactivity da m tsangwama.

Tsanaki

• Wannan samfurin an yi shi ne don amfani da bincike kawai kuma bai dace da binciken asibiti ko aikace-aikacen warkewa ba.

Karɓar samfurin bisa ga umarnin da aka bayar don kiyaye ayyukan furotin da mutunci.

Don kowace matsala ko tambayoyi game da samfurin, da fatan za a tuntuɓi ƙungiyar tallafin fasaha.

Cytokines
Mai watsa shiri Magana	Kwayoyin HEK293
Synonymous	GM-CSF, CSF2, MGC131935
Jerin sunadaran	NP_000749.2:A18-E144 an bayyana shi tare da alamar sa a C-terminus.
Molecular Mass	Yana tsinkayar adadin kwayoyin halitta na 15.3kD.
Tsaftar Gwajin QC	> 90% kamar yadda SDS-PAGE ya ƙaddara.
Endotoxin
Ayyuka	An auna ta hanyar haɓakar dogaro da kashi na haɓakar ƙwayoyin TF-1, takamaiman aikin shine ≥5.0 × 10⁶IU/mg.
Tsarin tsari	Lyophilized daga PBS mara kyau, pH 7.4. Yawanci kashi 6% na mannitol ana ƙara su azaman masu kariya kafin lyophilization.
Kwanciyar hankali	Ana iya adana shirye-shiryen Lyophilized a -20 ℃. 6 watanni a -20 ℃ a karkashin bakararre yanayi bayan reconstitution. 12 watanni a -80 ℃ a karkashin bakararre yanayi bayan sake gyarawa.
Adanawa	Shawarwari don raba furotin a cikin ƙananan ƙididdiga bayan sake haɗawa da ruwa don allura, saline na al'ada ko PBS, da kuma kiyaye ƙwayar da aka lalata sama da 100μg/mL. Guji maimaita daskarewa-narkewa.