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GMP-TL101 Anti-Human CD3 mAb Antigen paub, teeb liab hloov thiab T cell ua kom
Product Overview
Anti-Human CD3 mAb (GMP TL101) yog engineered los pab txhawb antigen paub, teeb liab transduction, thiab T cell activation. Cov tshuaj tiv thaiv kab mob monoclonal no yog ib qho tseem ceeb rau kev tshawb fawb thiab kev siv tshuaj kho mob nrog T cell manipulation.
Cov yam ntxwv tseem ceeb
● Kev Hloov Teeb Meem: Ua kom muaj txiaj ntsig zoo ntawm kev paub txog antigen thiab cov teeb liab hloov, tseem ceeb heev rau kev ua kom T cell.
● GMP Manufacturing: Ua nyob rau hauv nruj GMP tej yam kev mob los xyuas kom meej cov khoom zoo thiab reproducibility.
● High Specificity: High Specificity rau CD3, xyuas kom meej lub hom phiaj thiab tsawg kawg nkaus off-target los.
● Kev siv dav dav: Haum rau ntau yam kev siv, suav nrog cytometry ntws, kab lis kev cai ntawm tes, thiab kev tshawb fawb kho mob.
Daim ntawv thov
● Kev Tshawb Fawb Txog Kev Tiv Thaiv: Qhov tseem ceeb rau kev kawm T cell receptor (TCR) kev taw qhia thiab kev ua kom muaj zog.
● Kev Txhim Kho Kev Kho Mob: Pab txhim kho T cell-raws li kev kho mob, suav nrog kev kho CAR-T.
● Kev Tshawb Fawb Kev Tshawb Fawb: Tsim nyog rau cov txheej txheem tshawb fawb soj ntsuam uas xav tau cov khoom zoo, GMP-raws li cov tshuaj tiv thaiv.
Specifications thiab Ntim
● Specifications:
Muaj nyob rau hauv ntau qhov ntau thiab tsawg kom haum rau ntau qhov kev sim xav tau: 100μg, 500μg, thiab 1mg.
Cov qauv zoo ua kom muaj kev sib xws thiab kev ntseeg tau.
● Ntim:
Muab los ua kua tsis muaj menyuam lossis lyophilized hmoov kom yooj yim siv thiab khaws cia yooj yim.
Ntim kom muaj kev ncaj ncees thiab ua haujlwm zoo thaum thauj thiab tuav.
Cia thiab ruaj khov
Cia
Rau kev siv sijhawm luv, khaws cia ntawm 2-8 ° C.
Rau lub sijhawm ntev cia, khaws cia ntawm -20 ° C kom khaws cov tshuaj tiv thaiv kab mob thiab kev ua haujlwm.
Tsis txhob rov khov-thaw cycles kom tsis txhob degradation.
Kev ruaj ntseg
Ua kom ruaj khov raws li kev pom zoo khaws cia, ua kom ntseeg tau tias kev ua tau zoo hauv kev tshawb fawb siv.
Tsim los rau durability, lav kev ua haujlwm ntev.
Cov lus qhia rau kev siv
Dilute cov tshuaj tiv thaiv nyob rau hauv ib qho tsis haum lossis nruab nrab ua ntej siv.
Npaj thiab siv cov kev daws teeb meem raws li kev sim xav tau kom raug thiab rov tsim dua tshiab.
Ua raws li cov txheej txheem cuam tshuam rau koj daim ntawv thov, txawm tias nws yog cytometry ntws, immunohistochemistry, lossis kev soj ntsuam ua haujlwm.
Ceeb toom
• Cov khoom no yog tsim los rau kev tshawb fawb siv thiab tsis haum rau kev kuaj mob lossis kev siv tshuaj kho mob.
• Kuaj cov tshuaj tiv thaiv kab mob raws li cov lus qhia kom tswj tau nws txoj haujlwm thiab kev ncaj ncees.
• Rau ib qho teeb meem lossis kev nug, thov hu rau peb pab neeg txhawb nqa kev pab.
• Ua kom zoo rau koj qhov kev tshawb fawb nrog peb cov tshuaj tiv thaiv kab mob ntau yam thiab txhim khu kev qha. Rau cov ncauj lus kom ntxaws txog cov khoom lag luam thiab kev txhawb nqa, mus saib peb lub vev xaib.
| Monoclonal Antibodies | |
| Daim ntawv thov | Soluble txoj kev: qhov concentration ntawm 500 ng / mL yog pom zoo, nyob rau hauv uas T cells tuaj yeem qhib tau thiab CD3⁺CD56⁺T hlwb tuaj yeem nthuav dav. |
| Kev ua si lom neeg | Kev khi tus nqi nrog Jurkat hlwb yuav tsum tsis pub tsawg dua 90% |
| Txheej txheej: | 10 mL PBS buffer (5μg / mL anti-tib neeg CD3) yog muab tso rau hauv lub hwj T75 ntawm 4 ° C thaum hmo ntuj. Thov tshem PBS thiab ntxuav lub raj mis nrog saline maj mam peb zaug ua ntej siv. |
| Endotoxin | |
| Expression Host | CHO hlwb |
| Kev tsim qauv | Muab raws li 0.22μm lim kua hauv PBS, PH 7.4 |
| Purification: | Protein A purified los ntawm cell culture supernatant |
| QC Test Purity | > 95% raws li kev txiav txim los ntawm SDS-PAGE |
| Stability & Cia | 24 lub hlis ntawm 2 ℃ to 8 ℃. Tsis txhob rov qab khov-thaw cycles |
| ntiv tes xoo | Cov ntaub ntawv |
 | GMP-TL101_SDS.pdf |
| GMP-TL101_Product Sheet.pdf |