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Recombinant Human IL-3 Protein
Product Overview
Recombinant Human Interleukin-3 (IL-3) is a crucial cytokine involved in the regulation of hematopoiesis, stimulating the proliferation and differentiation of various blood cells. IL-3 exerts its effects by binding to the IL-3 receptor, initiating signaling pathways that are essential for the development and function of the immune system. This makes it a valuable tool for research in immunology, hematology, and cell biology.
Key Features
1.High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%, ensuring the reliability and reproducibility of experimental results.
2.High Biological Activity: Verified through multiple activity assays, this product effectively induces the expected biological responses in target cells, suitable for a wide range of research applications.
3.Batch Consistency: Manufactured under strict production and quality control protocols to ensure high consistency between batches, reducing variability in experimental outcomes.
4.Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements and broadening its application scope in research.
Applications
• Hematology: Research the role of IL-3 in the regulation of blood cell production, providing insights into the mechanisms of hematopoiesis and potential therapeutic targets for hematological disorders.
• Immunology: Study the effects of IL-3 on immune cell development and function, exploring its implications in immune response and autoimmune diseases.
• Stem Cell Research: Utilize IL-3 in studies focusing on stem cell differentiation and proliferation, contributing to advancements in regenerative medicine.
• Cell Biology: Investigate the impact of IL-3 on cell signaling pathways, survival, and proliferation, aiding in a deeper understanding of cellular processes.
Specifications and Packaging
• Specifications: Available in various sizes to meet different experimental needs, including 10μg, 50μg, 100μg, and 1mg.
• Packaging: Supplied in sterile lyophilized form for ease of storage and transport.
Storage and Stability
• Storage: Store at -20°C or below to maintain product stability and activity. Avoid repeated freeze-thaw cycles to prevent protein degradation.
• Stability: Stable for long-term storage under recommended conditions, ensuring reliable performance in research applications.
Instructions for Use
1.Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.
2.Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.
3.Do not mix with other similar products to avoid cross-reactivity and potential interference.
Cautions
• This product is intended for research use only and is not suitable for clinical diagnostics or therapeutic applications.
• Handle the product according to provided instructions to preserve its activity and stability.
• Contact our technical support team if you encounter any issues or have questions regarding the product's use.
| Cytokines | |
| Expression Host | A DNA sequence encoding the human IL-3 (GenBank: AAA59146.1) was expressed with a His-tag at the C-terminus. |
| Synonym | StabilityStabilityStabilityStability |
| Protein Sequence | Protein SequenceProtein Sequence |
| Molecular Mass | Molecular MassMolecular Mass |
| QC Testing Purity | QC Testing PurityQC Testing Purity |
| Endotoxin | MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor |
| Activity | HEK293 cells |
| Formulation | The recombinant human IL-3 protein consists of 139 amino acids and predicts a molecular mass of 15.9 kD. |
| Stability | StabilityStabilityStabilityStability |
| Storage | StorageStorageStorage |
| Thumb | File information |
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GMP-TL511_Product Sheet.pdf |
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GMP-TL511_SDS.pdf |