GMP-TL112 Anti-Human CD20 mAb Induction e reriloeng ea B cell apoptosis

Stock: Ka Stock
Mohlala: GMP-TL502

Iteanye le rona

Tlhaloso

Data Figures

Sebopeho

Lifaele tsa Tokomane

CD20 ke molek'hule e khethehileng ea saena holim'a B lymphocyte 'me e hlahisoa ho feta 95% ea li-lymphocyte tsa B tse tloaelehileng kapa tse kotsi. Ha ho na polelo ea antigen ea CD20 liseleng tsa stem tsa hematopoietic, lisele tsa progenitor, le lisele tse ling tse tloaelehileng. E na le li-amino acid tse 297 tse boima ba molek'hule ea 33 kD. CD20 ha e na ho kenngoa ka hare kapa lisele tsa lisele ka mor'a ho tlama ka anti-CD20 mAb, e leng antigen e loketseng phekolo ea mafu a amanang le B lymphocyte. Anti-CD20 mAb e ka bolaea boholo ba lisele tsa lymphoma tse hlahisang limolek'hule tsa CD20 le lisele tse tloaelehileng tsa B. Lisele tse tloaelehileng tsa tlhaho tsa B ha li amehe ke anti-CD20 mAb 'me li ka tsosolosa B cell cell. Ka hona, li-anti-CD20 monoclonal antibodies li sebelisoa ka ho eketsehileng ho phekola mafu a amanang le lisele tsa B

Li-cytokine
QC Testing Bohloeki	> 90 % joalo ka ha ho laetsoe ke SDS-PAGE.
Endotoxin
Tlhamo	E fanoa e le tharollo e tlhotliloeng ea 0.22μm ho PBS, PH 7.4
Li-antibodies tsa Monoclonal
Mosebetsi oa likokoana-hloko	Sekhahla se tlamang le PBMCs
Expression Host	CHO lisele
Hloekiso:	Protein/ E hloekisitsoeng ho tsoa liseleng tsa setso se phahametseng tlhaho.
Botsitso & Polokelo	Likhoeli tse 24 ho 2 ℃ ho isa ho 8 ℃. Qoba makhetlo a mangata a ho qhibiliha a leqhoa.